Patients with acute ischemic stroke (AIS) are susceptible to acute myocardial infarction (AMI), which would lead to a dramatic increase of in-hospital mortality. We established and validated an easy-used model to stratify the risk of in-hospital AMI among AIS patients. Overall, 96,367 patients were included. In-hospital AMI occurred in 392 (0.41%) patients. The final model, named CTRAN, incorporated five predictors including the history of coronary heart disease, malignant tumor, renal insufficiency, age and baseline National Institutes of Health Stroke Scale (NIHSS) score. The CTRAN score was confirmed in the validation cohort using receiver operating characteristic curve, which yielded an area under the curve (AUC) of 0.758 (95% confidence interval [CI], 0.718-0.798). The CTRAN score could be a good tool for clinicians to identify AIS patients at high in-hospital AMI risk.

JACC: Asia Editor-in-Chief 

Jian’an Wang, MD, PhD, FACC

CME Editor 

Kenneth A. Ellenbogen, MD

Authors
Luowei Chen, PhD

Min Lou, MD, PhD

Important Dates

Date of Release: December 20, 2022
Term of Approval/Date of CME/MOC/ECME Expiration: December 19, 2023