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Challenges in Cardiovascular Evaluation and Management of Obese Patients: JACC State-of-the-Art Review (JACC February 2023-1)

Many unique clinical challenges accompany the diagnosis and treatment of cardiovascular disease (CVD) in people living with overweight/obesity. Similarly, physicians encounter numerous complicating factors when managing obesity among people with CVD. Diagnostic accuracy in CVD medicine can be hampered by the presence of obesity and pharmacological treatments or cardiac procedures require careful adjustment to optimize efficacy. The obesity paradox concept remains a source of confusion within the clinical community that may cause important risk factors to go unaddressed and body mass index is a misleading measure that cannot account for body composition (e.g., lean mass). Lifestyle modifications that support weight loss require long-term commitment, but cardiac rehabilitation programs represent a potential opportunity for structured interventions and bariatric surgery may reduce CVD risk factors in obesity and CVD. This review examines the key issues and considerations for physicians involved in the management of concurrent obesity and CVD.


Valentin Fuster, MD, PhD, MACC

CME Editor
Ragavendra R. Baliga, MD

Rosana G. Bianchettin, MD
Carl J. Lavie, MD
Francisco Lopez-Jimenez, MD 

Important Dates
Date of Release: January 30, 2023

Term of Approval/Date of CME/MOC Expiration: January 29, 2024

Availability: On-Demand
Expires on Jan 29, 2024
Cost: FREE
Credit Offered:
1 CME Credit
1 ABIM-MOC Point
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