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Cardiac Disease in Childhood Cancer Survivors: Risk Prediction, Prevention, and Surveillance (JACC: CardioOncology September 2020)
Childhood Cancer Survivors: Risk Prediction, Prevention, and Surveillance (JACC: CardioOncology September 2020)
Cardiac diseases in the growing population of childhood cancer survivors are of major concern. Cardiotoxicity as a consequence of anthracyclines and chest radiotherapy continues to be relevant in the modern treatment era. Mitoxantrone has emerged as an important treatment-related risk factor and evidence on traditional cardiovascular risk factors in childhood cancer survivors is accumulating. International surveillance guidelines have been developed with the aim to detect and manage cardiac diseases early and prevent symptomatic disease. There is growing interest in risk prediction models to individualize prevention and surveillance. This State-of-the-Art Review summarizes literature from a systematic PubMed search focused on cardiac diseases after treatment for childhood cancer. Here, we discuss the prevalence, risk factors, prevention, risk prediction, and surveillance of cardiac diseases in survivors of childhood cancer.

JACC CardioOncology Editor-in-Chief and CME Editor
Bonnie Ky, MD, MSCE, FACC

Authors
Jan M. Leerink, MD
Esmée C. de Baat, MD
Elizabeth A.M. Feijen, PHD
Louise Bellersen, MD
Elvira C. van Dalen, MD, PHD
Heynric B. Grotenhuis, MD, PHD
Livia Kapusta, MD, PHD
Wouter E.M. Kok, MD, PHD
Jacqueline Loonen, MD, PHD
Heleen J.H. van der Pal, MD, PHD
Saskia M.F. Pluijm, PHD
Arco J. Teske, MD, PHD
Annelies M.C. Mavinkurve-Groothuis, MD, PHD
Remy Merkx, MD,
Leontien C.M. Kremer, MD, PHD

Important Dates

Date of Release: September 15, 2020
Term of Approval/Date of CME/MOC/ECME Expiration: September 14, 2021

Summary
Availability: On-Demand
Available Sep 15, 2020 to Sep 14, 2021
Cost: FREE
Credit Offered: 1 CME Credit
1 ABIM-MOC Point
1 ECME Credit
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