Beyond DOACs: Exploring the Promise of Factor XI Inhibitors in Cardiovascular Care

What You Will Learn

  • Define the hemostasis and thrombosis.
  • Compare and contrast the mechanisms of action of direct oral anticoagulants (DOACs) and investigational Factor XI inhibitors.  
  • Explain DOACs and Factor XI inhibitors’ implications for thromboembolic risk and bleeding profile.
  • Evaluate clinical trial data on the safety and efficacy of FXI inhibitors in various cardiovascular conditions, including AF, and secondary stoke prevention. 

Web-Based Lesson

 

We are grateful to these distinguished faculty who contributed to this collection:

Chair

Geoffrey D. Barnes, MD, MSc, FACC

Educational Grant Support Provided By: Bristol Myers Squibb and Janssen Pharmaceuticals, Inc., Alliance 

Page Launched: March 2026

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