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The Clinical Challenge of Prosthetic Valve Endocarditis: JACC Focus Seminar 3/4 (JACC April 2024-2)
During the past 6 decades, there have been numerous changes in prosthetic valve endocarditis (PVE), currently affecting an older population and increasing in incidence in patients with transcatheter-implanted valves. Significant microbiologic (molecular biology) and imaging diagnostic (fluorine-18 fluorodeoxyglucose-positron emission tomography/computed tomography) advances have been incorporated into the 2023 Duke-International Society for Cardiovascular Infectious Diseases infective endocarditis diagnostic criteria, thus increasing the diagnostic sensitivity for PVE without sacrificing specificity in validation studies. PVE is a life-threatening disease requiring management by multidisciplinary endocarditis teams in cardiac centers to improve outcomes. Novel surgical options are now available, and an increasing set of patients may avoid surgical intervention despite indication. Selected patients may complete parenteral or oral antimicrobial treatment at home. Finally, patients with prosthetic valves implanted surgically or by the transcatheter approach are candidates for antibiotic prophylaxis before invasive dental procedures.

Valentin Fuster, MD, PhD, MACC

CME Editor
Ragavendra R. Baliga, MD

Maan Malahfji, MD, FACC 

Important Dates
Date of Release: April 8, 2024
Term of Approval/Date of CME/MOC Expiration: April 7, 2025
Availability: On-Demand
Expires on Apr 07, 2025
Cost: FREE
Credit Offered:
1 CME Credit
1 ABIM-MOC Point
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