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Postinfarction Ventricular Septal Rupture: Identification of the Failure Mechanism of a Percutaneous Closure Procedure (JACC: Case Reports March 2022-1)

Ventricular septal rupture (VSR) is a rare but highly lethal (w60%) mechanical complication of myocardial infarction (MI). Although surgical repair has been the gold standard to correct the structural anomaly, percutaneous closure of the defect may represent a valuable therapeutic alternative, with the advantage of immediate shunt reduction to prevent further hemodynamic deterioration in patients with prohibitive surgical risk. Nonetheless, catheter-based VSR closure has faced certain drawbacks that have hampered its application. We describe a clinical case of postinfarction VSR treated with a percutaneous closure device and discuss the procedure’s failure mechanism.

JACC Editor-in-Chief 
Julia Grapsa, MD, PhD, FACC

CME Editor 
Nadeen N. Faza, MD, FACC

Juan P. Bachini, MD
Juan Torrado, MD, PhD

Important Dates

Date of Release: March 2, 2022
Term of Approval/Date of CME/MOC/ECME Expiration: March 1, 2023

Availability: On-Demand
Expires on Mar 01, 2023
Cost: FREE
Credit Offered:
1 CME Credit
1 ABIM-MOC Point
1 ECME Credit
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