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Brugada Syndrome as a Major Cause of Sudden Cardiac Death in Asians (JACC Asia August 2022)
Brugada Syndrome as a Major Cause of Sudden Cardiac Death in Asians

Brugada syndrome (BrS) is one of the main inherited arrhythmia syndromes causing ventricular fibrillation (VF) and sudden cardiac death in young to middle-aged men, especially in Asians. The diagnosis of BrS is based on spontaneous or drug provocated type 1 Brugada electrocardiogram. The current reliable therapy for BrS patients with VF history is the implantation of an implantable cardioverter-defibrillator. As for BrS patients without VF history, how asymptomatic BrS patients should effectively be treated is still uncertain because risk stratification of the BrS is still inadequate. Various parameters and combinations of several parameters have been reported for risk stratification of BrS. The SCN5A gene is believed to be only gene which is responsible for BrS, and has been reported to be useful for risk stratification. This review focuses on risk stratification of BrS patients, and focuses specifically on BrS patients of Asian descent.

JACC: Asia Editor-in-Chief 
Jian’an Wang, MD, PhD, FACC

CME Editor 
Kenneth A. Ellenbogen, MD


Yukiko Nakano, MD, PhD
Wataru Shimizu, MD, PhD

Important Dates

Date of Release: August 16, 2022
Term of Approval/Date of CME/MOC/ECME Expiration: August 15, 2023


Availability: On-Demand
Expires on Aug 15, 2023
Cost: FREE
Credit Offered:
1 CME Credit
1 ABIM-MOC Point
1 ECME Credit
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