Rapid Review Afib: The Latest in Management Strategies - Clinical Spotlight Meeting on Demand-Non-Pharmacologic Alternatives to Anticoagulation

Non-Pharmacologic Alternatives to Anticoagulation

Video Transcription

Video Summary

The video discusses alternatives to anticoagulation for stroke prophylaxis in atrial fibrillation (AFib), focusing on left atrial appendage occluder devices. The speaker highlights the data supporting the use of these devices and their limitations. They mention the PROTECT-AF study, which compared the Watchman device to warfarin and found a 39% lower risk of stroke with the device. The combined data of major bleed showed a 71% reduction with the device. The speaker also discusses the Amulet device, which was compared to Watchman in a head-to-head trial and showed similar efficacy and safety. The Amulet device had a significantly higher rate of left atrial occlusion. Both devices have low complication rates and further research is needed to determine device selection.

Keywords

anticoagulation

stroke prophylaxis

left atrial appendage occluder devices

PROTECT-AF study

Amulet device