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Rapid Review Afib: The Latest in Management Strate ...
Non-Pharmacologic Alternatives to Anticoagulation
Non-Pharmacologic Alternatives to Anticoagulation
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Video Transcription
Video Summary
The video discusses alternatives to anticoagulation for stroke prophylaxis in atrial fibrillation (AFib), focusing on left atrial appendage occluder devices. The speaker highlights the data supporting the use of these devices and their limitations. They mention the PROTECT-AF study, which compared the Watchman device to warfarin and found a 39% lower risk of stroke with the device. The combined data of major bleed showed a 71% reduction with the device. The speaker also discusses the Amulet device, which was compared to Watchman in a head-to-head trial and showed similar efficacy and safety. The Amulet device had a significantly higher rate of left atrial occlusion. Both devices have low complication rates and further research is needed to determine device selection.
Keywords
anticoagulation
stroke prophylaxis
left atrial appendage occluder devices
PROTECT-AF study
Amulet device
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