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Determinants of Ventricular Arrhythmias in Mitral ...
Article: Determinants of Ventricular Arrhythmias i ...
Article: Determinants of Ventricular Arrhythmias in Mitral Valve Prolapse
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The study investigated determinants of ventricular arrhythmias in mitral valve prolapse (MVP) patients without significant regurgitation and found that patients with arrhythmic MVP displayed higher mitral annulus disjunction, curling, and left ventricular fibrosis. Severe morphological, mechanical, and tissue alterations were linked to arrhythmias with a right bundle branch block pattern. Systolic curling was found to play a significant role in arrhythmogenesis, while mitral annulus disjunction's effect on arrhythmias was mediated by fibrosis. The study emphasized evaluating morphological, mechanical, and tissue abnormalities to understand ventricular arrhythmias in MVP patients with a right bundle branch block morphology. The complex interplay of these factors contributes to arrhythmias in MVP patients. The research suggests a correlation between mechanical abnormalities and fibrosis in arrhythmogenesis and provides insights into risk stratification, diagnosis, management, and potential surgical approaches for arrhythmic MVP patients.
Keywords
ventricular arrhythmias
mitral valve prolapse
MVP patients
mitral annulus disjunction
left ventricular fibrosis
arrhythmic MVP
right bundle branch block pattern
systolic curling
mechanical abnormalities
risk stratification
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